| Rank | Team | Wins | Losses | Runs Scored | Runs Allowed | Bill James | Difference | Combined |
|---|---|---|---|---|---|---|---|---|
| 1 | Los Angeles Dodgers | 111 | 51 | 847 | 513 | 115.95 | -4.95 | 140.092 |
| 2 | Houston Astros | 106 | 56 | 737 | 518 | 105.871 | 0.129 | 130.785 |
| 3 | New York Yankees | 99 | 63 | 807 | 567 | 106.506 | -7.506 | 126.856 |
| 4 | Atlanta Braves | 101 | 61 | 789 | 609 | 100.101 | 0.899 | 124.136 |
| 5 | New York Mets | 101 | 61 | 772 | 606 | 98.829 | 2.171 | 123.351 |
| 6 | St. Louis Cardinals | 93 | 69 | 772 | 637 | 95.33 | -2.33 | 116.253 |
| 7 | Toronto Blue Jays | 92 | 70 | 775 | 679 | 91.003 | 0.997 | 112.965 |
| 8 | Cleveland Guardians | 92 | 70 | 698 | 634 | 88.112 | 3.888 | 111.180 |
| 9 | Seattle Mariners | 90 | 72 | 690 | 623 | 88.52 | 1.48 | 110.198 |
| 10 | San Diego Padres | 89 | 73 | 705 | 660 | 85.919 | 3.081 | 107.974 |
| 11 | Philadelphia Phillies | 87 | 75 | 747 | 685 | 87.545 | -0.545 | 107.744 |
| 12 | Tampa Bay Rays | 86 | 76 | 666 | 614 | 86.948 | -0.948 | 106.758 |
| 13 | Milwaukee Brewers | 86 | 76 | 725 | 688 | 84.947 | 1.053 | 105.523 |
| 14 | San Francisco Giants | 81 | 81 | 716 | 697 | 83.028 | -2.028 | 101.252 |
| 15 | Baltimore Orioles | 83 | 79 | 674 | 688 | 79.466 | 3.534 | 100.288 |
| 16 | Minnesota Twins | 78 | 84 | 696 | 684 | 82.302 | -4.302 | 98.952 |
| 17 | Chicago White Sox | 81 | 81 | 686 | 717 | 77.676 | 3.324 | 97.948 |
| 18 | Boston Red Sox | 78 | 84 | 735 | 787 | 75.742 | 2.258 | 94.902 |
| 19 | Arizona Diamondbacks | 74 | 88 | 702 | 740 | 77.005 | -3.005 | 93.213 |
| 20 | Los Angeles Angels | 73 | 89 | 623 | 668 | 75.882 | -2.882 | 91.903 |
| 21 | Chicago Cubs | 74 | 88 | 657 | 731 | 73.019 | 0.981 | 90.752 |
| 22 | Texas Rangers | 68 | 94 | 707 | 743 | 77.23 | -9.23 | 89.648 |
| 23 | Miami Marlins | 69 | 93 | 586 | 676 | 70.627 | -1.627 | 86.190 |
| 24 | Colorado Rockies | 68 | 94 | 698 | 873 | 63.871 | 4.129 | 81.402 |
| 25 | Detroit Tigers | 66 | 96 | 557 | 713 | 63.236 | 2.764 | 79.775 |
| 26 | Kansas City Royals | 65 | 97 | 640 | 810 | 63.39 | 1.61 | 79.253 |
| 27 | Cincinnati Reds | 62 | 100 | 648 | 815 | 63.801 | -1.801 | 77.655 |
| 28 | Pittsburgh Pirates | 62 | 100 | 591 | 817 | 57.318 | 4.682 | 73.653 |
| 29 | Oakland Athletics | 60 | 102 | 568 | 770 | 58.98 | 1.02 | 73.444 |
| 30 | Washington Nationals | 55 | 107 | 603 | 855 | 55.344 | -0.344 | 68.114 |