| Rank | Team | Wins | Losses | Runs Scored | Runs Allowed | Bill James | Difference | Combined |
|---|---|---|---|---|---|---|---|---|
| 1 | Arizona Diamondbacks | 100 | 62 | 908 | 676 | 103.393 | -3.393 | 125.551 |
| 2 | Atlanta Braves | 103 | 59 | 840 | 661 | 99.078 | 3.922 | 124.739 |
| 3 | New York Yankees | 98 | 64 | 900 | 731 | 97.124 | 0.876 | 120.447 |
| 4 | Houston Astros | 97 | 65 | 823 | 675 | 96.026 | 0.974 | 119.152 |
| 5 | Cincinnati Reds | 96 | 67 | 865 | 711 | 96.644 | -0.644 | 118.186 |
| 6 | New York Mets | 97 | 66 | 853 | 711 | 95.557 | 1.443 | 118.133 |
| 7 | Cleveland Indians | 97 | 65 | 1009 | 860 | 93.944 | 3.056 | 117.867 |
| 8 | Boston Red Sox | 94 | 68 | 836 | 718 | 92.709 | 1.291 | 115.252 |
| 9 | Texas Rangers | 95 | 67 | 945 | 859 | 88.694 | 6.306 | 113.392 |
| 10 | Oakland Athletics | 87 | 75 | 893 | 846 | 85.323 | 1.677 | 106.372 |
| 11 | San Francisco Giants | 86 | 76 | 872 | 831 | 84.829 | 1.171 | 105.450 |
| 12 | Toronto Blue Jays | 84 | 78 | 883 | 862 | 82.928 | 1.072 | 103.042 |
| 13 | Baltimore Orioles | 78 | 84 | 851 | 815 | 84.415 | -6.415 | 100.256 |
| 14 | Pittsburgh Pirates | 78 | 83 | 775 | 782 | 79.806 | -1.806 | 98.016 |
| 15 | Los Angeles Dodgers | 77 | 85 | 793 | 787 | 81.591 | -4.591 | 97.896 |
| 16 | Philadelphia Phillies | 77 | 85 | 841 | 846 | 80.53 | -3.53 | 97.241 |
| 17 | Seattle Mariners | 79 | 83 | 859 | 905 | 76.811 | 2.189 | 96.180 |
| 18 | St. Louis Cardinals | 75 | 86 | 809 | 838 | 77.738 | -2.738 | 94.868 |
| 19 | Milwaukee Brewers | 74 | 87 | 815 | 886 | 73.901 | 0.099 | 91.864 |
| 20 | San Diego Padres | 74 | 88 | 710 | 781 | 73.721 | 0.279 | 91.186 |
| 21 | Chicago White Sox | 75 | 86 | 777 | 870 | 71.667 | 3.333 | 91.097 |
| 22 | Colorado Rockies | 72 | 90 | 906 | 1028 | 70.633 | 1.367 | 88.045 |
| 23 | Kansas City Royals | 64 | 97 | 856 | 921 | 74.642 | -10.642 | 86.113 |
| 24 | Anaheim Angels | 70 | 92 | 711 | 826 | 69.497 | 0.503 | 86.109 |
| 25 | Detroit Tigers | 69 | 92 | 747 | 882 | 67.62 | 1.38 | 84.857 |
| 26 | Tampa Bay Devil Rays | 69 | 93 | 772 | 913 | 67.813 | 1.187 | 84.453 |
| 27 | Montreal Expos | 68 | 94 | 718 | 853 | 67.727 | 0.273 | 83.782 |
| 28 | Chicago Cubs | 67 | 95 | 747 | 920 | 64.752 | 2.248 | 81.328 |
| 29 | Florida Marlins | 64 | 98 | 691 | 852 | 65.015 | -1.015 | 79.639 |
| 30 | Minnesota Twins | 63 | 97 | 686 | 845 | 64.264 | -1.264 | 79.540 |